GB 16230-1996 Hygienic standard for isopropyl alcohol in workshop air

This standard specifies the maximum permissible concentration of isopropyl alcohol in the air of a workshop and its monitoring and inspection methods. This standard applies to all types of enterprises that produce and use isopropyl alcohol. GB 16230-1996 Hygienic Standard for Isopropyl Alcohol in Workshop Air GB16230-1996 Standard download decompression password: www.bzxz.net

National Standard of the People's Republic of China
Health standard for isopropyl alcohol (IPA) in the air of workplace Subject content and scope of application
This standard specifies the maximum permissible concentration of isopropyl alcohol in the air of the workplace and its monitoring and inspection methods. This standard applies to all types of enterprises that produce and use isopropyl alcohol. Hygiene requirements
The maximum permissible concentration of isopropyl alcohol in the air of the workplace is 750mg/m. Monitoring and inspection methods
The monitoring and inspection methods of this standard adopt gas chromatography, see Appendix A (supplement). Approved by the State Technical Supervision Commission on April 3, 1996 526
GB16230-1996bZxz.net
Implementation on September 1, 1996
A1 Principle
GB 162301996
Appendix A
Gas chromatography
(Supplement)
Isopropyl alcohol in the air is collected by activated carbon tube, desorbed by solvent, separated by FFAP column, and detected by hydrogen flame ionization detector. The retention time is used for qualitative analysis and the peak height is used for quantitative analysis.
A2 Instrument
A2.1 Activated carbon tube, a glass tube with a length of 70mm and an inner diameter of 3.5-4mm. Fill it with activated carbon (A3.1) and divide it into two sections, front and back. The front section is 100mg, the back section is 50mg, and the middle is separated by glass wool. The two ends are fixed with glass wool and sealed for use. A2.2 Individual sampler.
A2.3 Gas chromatograph, hydrogen flame ionization detector. Chromatographic conditions: 2m long chromatographic column, 3mm inner diameter stainless steel column, FFAP stationary phase, ChromosorbW-AW support = 10:100, column temperature 70℃, detection chamber temperature 180℃, vaporization chamber temperature 180℃, carrier gas (N2) 35mL/min, hydrogen 40mL/min, air 600mL/min.
A3 Reagents
A3.1 Activated carbon: 20~40 mesh, treated with nitrogen at 300~350℃ for 4h before use. A3.2 Isopropanol: chromatographic grade.
A3.3 Desorption solvent: 1% isobutanol in carbon disulfide solution. A3.4 FFAP chromatographic stationary phase,
A3.5 ChromosorbW-AW support: 60~80 mesh. A4 Sampling
Open both ends of the sampling tube at the sampling site, place it vertically and connect it to the sampler. Draw 2L of air at a speed of 0.2L/min. After sampling, put plastic caps on both ends of the tube. The sample can be stored at room temperature for at least 7 days. A5 Analysis steps
A5.1 Control test: At the sampling site, operate the same sample, but do not sample air. A5.2 Sample treatment: Pour the activated carbon in the front and back sections of the sampling tube into 5mL stoppered colorimetric tubes, add 1mL of desorption solvent, plug the tubes tightly, and leave for 1h (shake several times in the middle). A5.3 Drawing of standard deduction curve: First add a small amount of desorption solvent to a 5mL volumetric flask, add a certain amount of isopropanol (1mL weighs 0.789g at 20℃), and accurately weigh the amount of isopropanol with an analytical balance. Add desorption solvent to the scale. Prepare a stock solution of a certain concentration. Before use, take a certain amount of stock solution and dilute it with desorption solution to form standard solutions with isopropanol contents of 1.0, 4.0 and 10 μg/uL, respectively. Take 1 μL of each solution for injection, measure the retention time and peak height, repeat 3 times for each concentration, take the average of the peak height, plot the isopropanol content against the peak height, draw a standard curve, and use the retention time as a qualitative indicator.
A5.4 Determination: Take 1 μL of sample desorption solution for injection, use the retention time for qualitative analysis and the peak height for quantitative analysis. 527
A6 Calculation
GB16230—1996
C±C2×1 000
Where: X isopropanol concentration in air, mg/m2; Ci, C2 are the isopropanol contents in the two activated carbon desorption solutions before and after, μg; V.
Convert to the sampling volume under standard conditions, L. A7 Notes
A7.1 The detection limit of this method is 4.1×10-4μg (1μL solution injection), the standard curve range is 0～10μg, and the regression equation is: y=46.4z—1.6, r=0.999. The coefficient of variation of this method is between 1.8% and 2.4%. A7.2 The desorption efficiency of this method is greater than 96%.
A7.3 The penetration capacity of this method is 9.12mg. When sampling under high relative humidity, the penetration capacity of the activated carbon adsorbent will be significantly reduced. At this time, a suitable drying tube should be connected to reduce the humidity. A7.4 This method can distinguish other organic solvents such as isobutyl alcohol and xylene, and does not interfere with the determination of isopropyl alcohol, see the figure below. However, the retention time of ethyl acetate, ethanol and benzene is close to that of isopropyl alcohol. If these substances are present on site, the chromatographic conditions should be changed to exclude them. Next
Lifting two alcohols
Time, min
Isopropanol on-site sample chromatogram
Additional notes:
GB16230
This standard is proposed by the Ministry of Health of the People's Republic of China. This standard is drafted by the Labor Hygiene Teaching and Research Section of the School of Public Health of Shanghai Medical University. The main drafters of this standard are Lu Qiming, Hu Jinghu, and Liang Youxin. This standard is interpreted by the Institute of Labor Hygiene and Occupational Diseases of the Chinese Academy of Preventive Medicine, which is entrusted by the Ministry of Health. 529
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