GB 17016-1997 Diagnostic criteria and management principles for mumps

This standard specifies the diagnostic criteria and treatment principles for mumps. This standard applies to the diagnosis, reporting and treatment of mumps by all levels and types of medical care and epidemic prevention institutions across the country. GB 17016-1997 Diagnostic Criteria and Treatment Principles for Mumps GB17016-1997 Standard Download Decompression Password: www.bzxz.net

(GB170161997
Diagnostic criteria and treatment principles for mumps Preface
Mumps is an acute respiratory infectious disease caused by the mumps virus. It is distributed worldwide and is classified as a statutory infectious disease in my country. It can occur throughout the year, with a peak in winter and spring. It is more common in children and is sporadic or epidemic. It can form an outbreak in collective children's institutions. Clinically, it is characterized by acute non-suppurative swelling of the parotid glands, often accompanied by meningitis, pancreatitis and orchitis. In order to better guide the prevention and control work, the diagnostic criteria and treatment principles of this disease are specially formulated. This standard is proposed by the Ministry of Health of the People's Republic of China. This standard is drafted by Tianjin Infectious Disease Hospital. Drafters of this standard: Cao Wukui, Zou Huan This standard is interpreted by the Chinese Academy of Preventive Medicine, the technical coordination unit entrusted by the Ministry of Health. 1 Scope
This standard specifies the diagnostic criteria and treatment principles of mumps. This standard applies to the diagnosis, reporting and treatment of mumps by all levels and types of medical care and health and epidemic prevention institutions across the country.
2 Diagnostic principles
Clinical diagnosis is mainly based on epidemiological history, enlargement of parotid glands and/or other salivary glands, and the diagnosis must be confirmed through serological and pathogenic tests.
3 Diagnostic criteria
31 Epidemiological history
History of contact with mumps patients 2 to 3 weeks before onset of the disease or local epidemic of the disease. 3.2 Symptoms and signs
3.2.1 Non-purulent swelling of the parotid or other glands. The pain and swelling are aggravated by eating acidic food. 3:2,2 Severe headache, drowsiness, vomiting, and positive signs of meningeal irritation. The cerebrospinal fluid shows non-purulent changes (similar to other viral encephalitis).
3.2.3 Nausea and vomiting, accompanied by pain and tenderness in the middle and upper abdomen, and local muscle tension. 3.2.4 Testicular swelling and pain (usually unilateral).
3.3 Laboratory tests
3.3.1 No live attenuated mumps vaccine has been administered within 11 months, and specific IgM antibodies are positive in serum. 3.3.2 The IgG antibody titer of two sera (2 to 4 weeks apart) is 4 times or more higher. 3.3.3 Parotitis was isolated from saliva, urine, cerebrospinal fluid, and blood. Adenovirus. 3.4 Case classification
3.4.1 Suspected cases:
a) with 3.2.1 or with 3.2.2 or 3.2.3 or 3.2.4; b) with 3.2.2 or 3.2.3 or 3.2.4 plus 3.1. 3.4.2 Clinically diagnosed cases: 3.4.1-1 plus 3.1. 3.4.3 Confirmed cases: Suspected cases or clinically diagnosed cases plus 3.3.1 or 3.3.2 or 3.3.3. 4 Treatment principles
4.1 General treatment and symptomatic treatment
4.1. 1 Pay attention to oral hygiene, eat a light diet, avoid acidic foods, drink plenty of water to ensure intake 2 For those with high fever, headache, and vomiting, give symptomatic treatment such as antipyretics, analgesics, and dehydration agents. 4.1.2
4.2 Treatment with Chinese medicine
4.2.1 Oral administration of Chinese medicine preparations to clear away heat and toxic substances, soften hard masses and relieve pain4.2.2 Local medication to relieve swelling and relieve pain.
4,3 Adrenocortical hormone treatment
Mainly used for severe cases or those with meningitis or orchitis. 4.4 Prevention
4.4.1 Early isolation of patients until the swelling of the cheeks subsides. Contacts generally do not need quarantine, and suspected patients should be temporarily isolated. 4.4.2
Mumps live attenuated vaccine or measles-rubella-mumps combined vaccine can be administered to susceptible populations. Appendix A
(Standard Appendix)
Virus Isolation
Specimen Collection and Processing
Collect fluid from the oral cavity of patients in the early stage of the disease (can also be collected from blood and urine, and the virus can be isolated from cerebrospinal fluid in patients with meningitis). To increase the amount of fluid, use a tongue depressor to gently press the parotid duct opening or gently stroke the swelling in the lower part of the ear. Spit directly into a small flat dish and add 1/2 of the fluid volume of Hanks liquid for centrifugation. Take the supernatant and add 500-1000U of penicillin and streptomycin and put it in the refrigerator for 2 hours. A2 Chicken Embryo Culture and Isolation MethodWww.bzxZ.net
Use the chicken embryo amniotic cavity inoculation method, take chicken embryos incubated for 7 to 9 days, inoculate 4 to 6 specimens, and inoculate each chicken embryo with 0.15 to 0.2mL, and then put it in a 36-37℃ incubator for 5 to 7 days. Discard those who died. The live chicken embryo is placed at 4℃ overnight to allow the blood to coagulate for several days. The amniotic fluid is harvested and tested for hemagglutination. If the test is positive and can be inhibited by the specific mumps immune serum, a diagnosis report can be made. If the test is negative, a complementation test can be performed again or the cells can be subcultured for two more times. If the test is still negative for the third time, the result is considered negative.
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